In a statement defending/ explaining her vote, Sinema slyly says, "I was a principled opponent of the Iraq War and spoke out early against the U.S. invasion." One must wonder if she considers some opponents unprincipled. But the more important fact was that back then she was a recent Green Party candidate for Phoenix City Council.
Since then, she climbed the ladder to the Legislature and then Congress as a Democrat. She frequently alienated the Democratic wing of the Democratic Party, such as when, serving in the state Senate, she called the odious Russell Pearce, "my president." He was president of the Senate, but "my president"?
On the Iran vote, Blog for Arizona commented, "Sinema’s excuses for opposition are on matters entirely outside of the negotiated nuclear agreement, and thus not on the merits of the actual agreement itself. Like every Tea-Publican, Sinema wants total capitulation by Iran, something Iran would never agree to in a negotiation. This is a ridiculous expectation."